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Vertex Pharmaceuticals Says Alyftrek Delivers Pancreatic Function Recovery in Some Children

Vertex Pharmaceuticals Says Alyftrek Delivers Pancreatic Function Recovery in Some Children

MT newswireMT newswire2026/10/09 18:01

02:01 PM EDT, 10/09/2026 (MT Newswires) -- Vertex Pharmaceuticals (VRTX) said Friday that new interim data from an open-label extension study evaluating Alyftrek in cystic fibrosis showed that some pediatric patients aged 2 to 5 years recovered exocrine pancreatic function, allowing them to discontinue pancreatic enzyme replacement therapy. Of 48 children enrolled in the pancreatic enzyme replacement therapy discontinuation substudy, 18, or 37.5%, stopped the therapy for a mean of 8.6 weeks after at least 48 weeks of treatment, the company said. Across the full 66-child cohort, 50% were not on the therapy at the time of the data cut, Vertex said. Price: 510.01, Change: +6.76, Percent Change: +1.34

02:01 PM EDT, 10/09/2026 (MT Newswires) -- Vertex Pharmaceuticals (VRTX) said Friday that new interim data from an open-label extension study evaluating Alyftrek in cystic fibrosis showed that some pediatric patients aged 2 to 5 years recovered exocrine pancreatic function, allowing them to discontinue pancreatic enzyme replacement therapy. Of 48 children enrolled in the pancreatic enzyme replacement therapy discontinuation substudy, 18, or 37.5%, stopped the therapy for a mean of 8.6 weeks after at least 48 weeks of treatment, the company said. Across the full 66-child cohort, 50% were not on the therapy at the time of the data cut, Vertex said. Price: 510.01, Change: +6.76, Percent Change: +1.34
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